Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7771812 | 1.00 | MAPT (0.45) | MAPTDNM1GPR84TRPV1KCNH2 | |
| SCHEMBL3452064 | 1.00 | MAPT (0.45) | MAPTDNM1GPR84TRPV1KCNH2 | |
| SCHEMBL7770559 | 1.00 | MAPT (0.45) | MAPTDNM1GPR84TRPV1KCNH2 | |
| SCHEMBL4767465 | 0.92 | MAPT (0.51) | MAPTGPR84TRPV1 | |
| SCHEMBL2444957 | 0.84 | MAPT (0.38) | MAPTTRPV1 | |
| SCHEMBL2460601 | 0.82 | DNM1 (0.38) | DNM1KCNH2NPC1JAK2RAB9A | |
| SCHEMBL9800597 | 0.82 | DNM1 (0.38) | DNM1KCNH2NPC1JAK2RAB9A | |
| SCHEMBL9800564 | 0.82 | DNM1 (0.38) | DNM1KCNH2NPC1JAK2RAB9A | |
| SCHEMBL94910 | 0.80 | NPC1 (0.51) | MAPTDNM1TRPV1KCNH2NPC1 | |
| SCHEMBL21916561 | 0.80 | NPC1 (0.51) | MAPTDNM1TRPV1KCNH2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623608-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0623608-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1994-11-09 | — | — | EP | disclosed |