SCHEMBL7863967

SCHEMBL7863967

CCc1c(Cl)cc(C(=O)O)c(Cl)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.40
ALDH1A1 P00352 6/20 0.38
TSHR P16473 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
TP53 P04637 1/20 0.38
CASP1 P29466 1/20 0.38
CLCN2 P51788 1/20 0.38
AKR1C4 P17516 1/20 0.37
AKR1C3 P42330 1/20 0.37
AKR1C2 P52895 1/20 0.37
AKR1C1 Q04828 1/20 0.37
KDM4E B2RXH2 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HPGD P15428 2/20 0.37
HSD17B10 Q99714 2/20 0.37
MAPT P10636 1/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
MRGPRX4 Q96LA9 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2149018 0.85 AKR1C2 (0.47) ALDH1A1TSHRSMN1; SMN2TP53CASP1
SCHEMBL542774 0.82 CYP3A4 (0.41) CYP3A4ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL21519775 0.81 MRGPRX4 (0.36) CYP3A4ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL4617979 0.78 AKR1C2 (0.47) CYP3A4ALDH1A1TSHRSMN1; SMN2CLCN2
SCHEMBL10397526 0.77 TSHR (0.47) ALDH1A1TSHRSMN1; SMN2TP53CASP1
SCHEMBL8743543 0.77 CYP3A4 (0.41) CYP3A4ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL1437003 0.74 CYP3A4 (0.48) CYP3A4ALDH1A1TSHRSMN1; SMN2TP53
SCHEMBL23531201 0.74 ALDH1A1 (0.36) ALDH1A1TSHRSMN1; SMN2TP53CASP1
SCHEMBL30280779 0.74 ALDH1A1 (0.36) ALDH1A1TSHRSMN1; SMN2TP53CASP1
SCHEMBL8856970 0.74 CLCN2 (0.40) ALDH1A1TSHRSMN1; SMN2TP53CASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6303812-B1 ADDING WATER TO A MIXTURE CONTAINING A CUPROUS HALIDE, CUPROUS ACETATE OR PROPIONATE, AND CERTAIN DEHALOGENATED AROMATIC PRODUCTS, SUCH AS METHYL 3,5-DICHLORO-4-METHYLBENZOATE, CAUSES THE MIXTURE TO SEPARATE INTO ORGANIC AND AQUEOUS PHASES OCCIDENTAL CHEMICAL CORPORATION 2001-10-16 US claimed
US-6303812-B1 ADDING WATER TO A MIXTURE CONTAINING A CUPROUS HALIDE, CUPROUS ACETATE OR PROPIONATE, AND CERTAIN DEHALOGENATED AROMATIC PRODUCTS, SUCH AS METHYL 3,5-DICHLORO-4-METHYLBENZOATE, CAUSES THE MIXTURE TO SEPARATE INTO ORGANIC AND AQUEOUS PHASES OCCIDENTAL CHEMICAL CORPORATION 2001-10-16 US disclosed