Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | PTGFR | P43088 | 4/20 | 0.48 |
| ▸ | TBXA2R | P21731 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.48 |
| ▸ | SLCO2A1 | Q92959 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.48 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6694590 | 0.93 | PDE4D (0.50) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6755613 | 0.88 | ALDH1A1 (0.52) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6691881 | 0.87 | PTGFR (0.50) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6692368 | 0.85 | PDE4D (0.42) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6691943 | 0.84 | PDE4D (0.39) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6693793 | 0.83 | ALDH1A1 (0.52) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6690486 | 0.83 | PDE4D (0.49) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6690724 | 0.83 | PDE4D (0.49) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL8579034 | 0.83 | PDE4D (0.49) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 | |
| SCHEMBL6696130 | 0.81 | PDE4D (0.45) | ALDH1A1PTGFRTBXA2RLMNAPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303658-B1 | THERAPY OF OCULAR HYPERTENSION BY APPLYING CYCLOPENTANE HEPTENOIC ACID OR HEPTANOIC ACID AND/OR DERIVATIVE | ALLERGAN SALES, INC. | 2001-10-16 | — | — | US | disclosed |