SCHEMBL7864080

SCHEMBL7864080

O=C(CCCC1CCCC1)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.58
TDP1 Q9NUW8 2/20 0.58
LMNA P02545 1/20 0.58
MAPT P10636 1/20 0.58
KMT2A Q03164 1/20 0.57
KDM4E B2RXH2 1/20 0.55
HDAC1 Q13547 6/20 0.53
HDAC8 Q9BY41 6/20 0.53
HDAC3 O15379 2/20 0.53
HDAC4 P56524 2/20 0.53
HDAC7 Q8WUI4 2/20 0.53
HDAC2 Q92769 2/20 0.53
HDAC10 Q969S8 2/20 0.53
HDAC11 Q96DB2 2/20 0.53
HDAC6 Q9UBN7 2/20 0.53
HDAC9 Q9UKV0 2/20 0.53
HDAC5 Q9UQL6 2/20 0.53
BCHE P06276 2/20 0.52
ACHE P22303 2/20 0.52
NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28946798 0.89 KMT2A (0.69) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL12315082 0.88 KMT2A (0.50) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL9395430 0.88 L3MBTL1 (0.66) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL2443481 0.88 KMT2A (0.68) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL13912376 0.88 KMT2A (0.68) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL7493236 0.86 KMT2A (0.69) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL13655425 0.85 L3MBTL1 (0.50) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL27832662 0.82 KMT2A (0.61) L3MBTL1TDP1MAPTKMT2AKDM4E
SCHEMBL13814798 0.82 BCHE (0.67) L3MBTL1TDP1LMNAMAPTKMT2A
SCHEMBL7287809 0.81 L3MBTL1 (0.56) L3MBTL1TDP1LMNAMAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0623608-B1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LTD (JP) 2001-05-30 EP disclosed
EP-0546177-B1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TEIJIN LTD (JP) 1998-01-07 EP disclosed
US-5574061-A ANTILIPEMIC AGENT, ANTIATHEROSCLEROSIS, ACAT INHIBITOR TEIJIN LIMITED (JP) 1996-11-12 US disclosed
EP-0623608-A1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 1994-11-09 EP disclosed
EP-0546177-A1 BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME TEIJIN LIMITED (JP) 1993-06-16 EP disclosed