Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.46 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7863017 | 0.90 | HTR2C (0.47) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL7503270 | 0.74 | MEN1 (0.64) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL24953351 | 0.73 | HTR2C (0.48) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL19405280 | 0.73 | PDE4B (0.64) | SMN1; SMN2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL14965438 | 0.72 | HTR2C (0.53) | HTR2CCACNA1GCACNA1HCACNA1ISMN1; SMN2 | |
| SCHEMBL3825312 | 0.72 | FFAR2 (0.52) | HTR2CRAB9AFFAR2HTT | |
| SCHEMBL3825310 | 0.72 | FFAR2 (0.52) | HTR2CRAB9AFFAR2HTT | |
| SCHEMBL13994810 | 0.72 | PREP (0.57) | MEN1KMT2AALDH1A1NPSR1TP53 | |
| SCHEMBL791439 | 0.72 | PREP (0.57) | MEN1KMT2AALDH1A1NPSR1TP53 | |
| SCHEMBL10251296 | 0.71 | SMN1; SMN2 (0.53) | HTR2CSMN1; SMN2NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300316-B1 | ANTIBIOTICS AS BACTERICIDE | PFIZER INC | 2001-10-09 | — | — | US | disclosed |
| US-6025350-A | C-4\" substituted macrolide antibiotics | PFIZER INC. (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0895999-A1 | C-4\" substituted macrolide antibiotics | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |