Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7591591 | 0.82 | TSHR (0.43) | CYP1A2CYP2C19CYP2D6KDM4EMEN1 | |
| SCHEMBL9244524 | 0.77 | TSHR (0.39) | CYP1A2CYP2C19CYP2D6KDM4EMEN1 | |
| SCHEMBL11360852 | 0.75 | MAPT (0.50) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL1538371 | 0.74 | MAPT (0.54) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL29377898 | 0.74 | MAPT (0.54) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL6035270 | 0.74 | MAPT (0.54) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL78554 | 0.72 | CA1 (0.52) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL28575044 | 0.72 | CA1 (0.52) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL29352478 | 0.72 | CA1 (0.52) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 | |
| SCHEMBL147382 | 0.71 | MAPT (0.47) | MAPTHTR1BCYP1A2CYP2C19L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0504418-B2 | PROCESS FOR PRODUCING CYCLOOLEFIN POLYMER AND CYCLOOLEFIN COPOLYMERS | IDEMITSU KOSAN CO (JP) | 2001-06-13 | — | — | EP | disclosed |