SCHEMBL7864396

SCHEMBL7864396

O=C(O)c1ccc(C(=O)O)c2c(C(=O)NO)ccc(C(=O)NO)c12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.67
MPO P05164 2/20 0.45
GAA P10253 2/20 0.45
KDM4E B2RXH2 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
HIF1A Q16665 1/20 0.45
HDAC7 Q8WUI4 4/20 0.44
HDAC8 Q9BY41 4/20 0.44
HDAC6 Q9UBN7 4/20 0.44
HDAC1 Q13547 3/20 0.44
HDAC2 Q92769 3/20 0.44
ALOX15 P16050 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HDAC3 O15379 2/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
IDO1 P14902 1/20 0.44
CA9 Q16790 1/20 0.44
NCOR2 Q9Y618 1/20 0.44
MMP3 P08254 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1025413 1.00 CYP1A2 (0.67) CYP1A2MPOGAAKDM4ESMN1; SMN2
SCHEMBL7864373 0.92 CYP1A2 (0.56) CYP1A2MPOGAAKDM4ESMN1; SMN2
SCHEMBL22122 0.82 CYP1A2 (1.00) CYP1A2GAAKDM4ESMN1; SMN2HDAC8
SCHEMBL29417502 0.82 CYP1A2 (1.00) CYP1A2GAAKDM4ESMN1; SMN2HDAC8
SCHEMBL1026340 0.81 HSD17B10 (0.60) CYP1A2MPOGAAKDM4ESMN1; SMN2
SCHEMBL4959993 0.79 CYP1A2 (0.64) CYP1A2GAASMN1; SMN2HDAC8HDAC6
SCHEMBL1538062 0.79 GAA (0.43) CYP1A2MPOGAAKDM4ESMN1; SMN2
SCHEMBL12021877 0.79 CYP1A2 (0.64) CYP1A2GAASMN1; SMN2HDAC8HDAC6
SCHEMBL823142 0.79 CYP1A2 (0.64) CYP1A2GAASMN1; SMN2HDAC8HDAC6
SCHEMBL1538065 0.79 GAA (0.43) CYP1A2MPOGAAKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6316639-B1 REACTING DICARBOXYLIC ACIDS OR ANHYDRIDES WITH A SALT OF HYDROXYL-AMINE IN SOLUTION SELECTED FROM HYDROXYLAMINE SULFATE, HYDROXYLAMINE NITRATE, HYDROXYLAMINE ACETATE, HYDROXYLAMINE TETRAFLUOROBORATE, HYDROXYLAMINE PHOSPHATE Consortium für elektrochemische Industrie GmbH (DE) 2001-11-13 US disclosed