SCHEMBL823142

SCHEMBL823142

CNC(=O)c1ccc(C(=O)O)c2c(C(=O)NC)ccc(C(=O)O)c12

nearest known ligand 0.64

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.64
GAA P10253 2/20 0.45
NEU3 Q9UQ49 1/20 0.45
PLK1 P53350 2/20 0.42
HDAC2 Q92769 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK10 P53779 1/20 0.39
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
HPGD P15428 1/20 0.38
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
APEX1 P27695 1/20 0.37
KDM4C Q9H3R0 1/20 0.37
BRD4 O60885 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4959993 1.00 CYP1A2 (0.64) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL12021877 1.00 CYP1A2 (0.64) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL11520918 0.92 CYP1A2 (0.54) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL2100060 0.92 CYP1A2 (0.54) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL823153 0.92 CYP1A2 (0.54) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL30101142 0.92 CYP1A2 (0.54) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL13302875 0.90 CYP1A2 (0.52) CYP1A2GAANEU3PLK1HDAC2
SCHEMBL9006369 0.89 CYP1A2 (0.50) CYP1A2GAANEU3PLK1ALDH1A1
SCHEMBL6783520 0.82 HSD17B10 (0.58) CYP1A2GAAPLK1ALDH1A1ALOX15
SCHEMBL12038232 0.80 CYP1A2 (0.41) CYP1A2GAANEU3PLK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8450726-B2 Articles containing coatings of amic acid salts EASTMAN KODAK COMPANY (US) 2013-05-28 US disclosed
US-8431433-B2 Methods of providing semiconductor layers from amic acid salts EASTMAN KODAK COMPANY (US) 2013-04-30 US disclosed
US-8404892-B2 Aromatic amic acid salts and compositions EASTMAN KODAK COMPANY (US) 2013-03-26 US disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS FPC INC. 2011-12-01 US disclosed
US-20110294257-A1 METHODS OF PROVIDING SEMICONDUCTOR LAYERS FROM AMIC ACID SALTS KODAK AMERICAS LTD. 2011-12-01 US disclosed
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS FPC INC. 2011-12-01 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137133-A2 SEMICONDUCTING DEVICES AND METHODS OF PREPARING EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137139-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110295010-A1 AROMATIC AMIC ACID SALTS AND COMPOSITIONS DDC, MYOC, TNNC1 CYP1A2 679/4885GAA 2763/4885NEU3 2809/4885
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC CYP1A2 498/4885GAA 2404/4885NEU3 3664/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC CYP1A2 155/4885GAA 2124/4885NEU3 2145/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.