Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.42 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854690 | 0.86 | LMNA (0.54) | KMT2ADRD3DRD2ALDH1A1 | |
| SCHEMBL7854688 | 0.83 | TBXA2R (0.54) | DRD3DRD2TBXA2RALDH1A1 | |
| SCHEMBL7861294 | 0.79 | DRD3 (0.60) | DRD3DRD2TBXA2R | |
| SCHEMBL7864498 | 0.79 | DRD3 (0.51) | KMT2ADRD3DRD2CA1CA2 | |
| SCHEMBL7860206 | 0.77 | CYP19A1 (0.54) | DRD3DRD2CA1CA2TBXA2R | |
| SCHEMBL7861583 | 0.76 | CYP19A1 (0.54) | DRD3DRD2TBXA2R | |
| SCHEMBL7861602 | 0.76 | CYP19A1 (0.53) | DRD3DRD2CA1CA2 | |
| SCHEMBL7411290 | 0.76 | DRD3 (0.67) | DRD3DRD2TBXA2R | |
| SCHEMBL7457363 | 0.76 | DRD3 (0.61) | KMT2ADRD3DRD2TBXA2R | |
| SCHEMBL7457371 | 0.76 | DRD3 (0.61) | KMT2ADRD3DRD2TBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0807101-B1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | UPJOHN CO (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5936000-A | 2-aminoindans as selective dopamine D3 ligands | PHARMACIA & UPJOHN COMPANY (US) | 1999-08-10 | — | — | US | disclosed |
| WO-1996023760-A1 | 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS | PHARMACIA & UPJOHN COMPANY (US) | 1996-08-08 | — | — | WO | disclosed |