Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.36 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867267 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7863584 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7863553 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7864525 | 1.00 | ALDH1A1 (0.38) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7856643 | 0.98 | ALDH1A1 (0.36) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7864338 | 0.92 | ALDH1A1 (0.37) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL15149813 | 0.82 | ALDH1A1 (0.39) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL3039671 | 0.78 | ALDH1A1 (0.41) | ALDH1A1USP2MAPTCYP3A4SMN1; SMN2 | |
| SCHEMBL7862186 | 0.78 | — | — | |
| SCHEMBL7862188 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067122-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-01-10 | — | — | EP | disclosed |
| EP-0435632-A2 | Phenylpyrimidine derivatives, process for preparing the same, liquid crystal compositions containing said derivatives as active ingredient, and liquid crystal elements using such compositions | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-07-03 | — | — | EP | disclosed |