Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.70 |
| ▸ | ADRB1 | P08588 | 11/20 | 0.70 |
| ▸ | ADRB2 | P07550 | 8/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7859235 | 0.82 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6906026 | 0.82 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7782074 | 0.81 | ADRB3 (0.71) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8867845 | 0.78 | ACACB (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8867839 | 0.78 | ACACB (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6906032 | 0.75 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7865755 | 0.75 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8999624 | 0.74 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 | |
| SCHEMBL5487743 | 0.74 | ADRB3 (0.81) | ADRB3ADRB1ADRB2 | |
| Rafabegron SCHEMBL678589 | 0.74 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0801059-B1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO (JP) | 2001-06-27 | — | — | EP | disclosed |
| EP-0801059-A1 | INDOLE DERIVATIVE | DAINIPPON PHARMACEUTICAL CO., LTD. (JP) | 1997-10-15 | — | — | EP | disclosed |