Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 20/20 | 0.71 |
| ▸ | ADRB1 | P08588 | 10/20 | 0.71 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7779180 | 0.90 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6906026 | 0.83 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7859235 | 0.83 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7864544 | 0.81 | ADRB3 (0.70) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8193136 | 0.76 | SLC2A1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL9240404 | 0.76 | SLC2A1 (0.47) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8999624 | 0.75 | ADRB3 (0.72) | ADRB3ADRB1ADRB2 | |
| SCHEMBL7870408 | 0.73 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL6911229 | 0.73 | ADRB3 (1.00) | ADRB3ADRB1ADRB2 | |
| SCHEMBL8710196 | 0.73 | ADRB3 (0.70) | ADRB3ADRB1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1128845-A1 | COMBINATIONS COMPRISING A BETA-AGONIST AND A FURTHER ANTDIABETIC AGENT | SMITHKLINE BEECHAM PLC (GB) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027434-A1 | COMBINATIONS COMPRISING A BETA-AGONIST AND A FURTHER ANTIDIABETIC AGENT | SMITHKLINE BEECHAM P.L.C. (GB) | 2000-05-18 | — | — | WO | disclosed |