Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 10/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860530 | 0.79 | FBP1 (0.67) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4135529 | 0.77 | FBP1 (0.80) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL7865214 | 0.77 | FBP1 (0.54) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4130111 | 0.75 | FBP1 (1.00) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4128973 | 0.72 | FBP1 (0.83) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4146195 | 0.72 | FBP1 (0.67) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4134494 | 0.72 | FBP1 (0.63) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4120627 | 0.71 | FBP1 (0.62) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4129141 | 0.69 | FBP1 (0.62) | FBP1ALDH1A1CYP1A2 | |
| SCHEMBL4129770 | 0.68 | FBP1 (0.58) | FBP1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1143955-A3 | A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES | Metabasis Therapeutics Inc. (US) | 2002-08-28 | — | — | EP | disclosed |
| EP-1143955-A2 | A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES | Metabasis Therapeutics Inc. (US) | 2001-10-17 | — | — | EP | disclosed |
| EP-1112275-A1 | NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE | Metabasis Therapeutics, Inc. (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000038666-A2 | A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES | METABASIS THERAPEUTICS, INC. (US) | 2000-07-06 | — | — | WO | disclosed |
| WO-2000014095-A1 | NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE | METABASIS THERAPEUTICS, INC. (US) | 2000-03-16 | — | — | WO | disclosed |