Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 16/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 8/20 | 0.39 |
| ▸ | IARS1 | P41252 | 1/20 | 0.35 |
| ▸ | FAP | Q12884 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7865250 | 1.00 | DPP4 (0.43) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL2783500 | 0.84 | DPP4 (0.47) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL5161688 | 0.82 | DPP4 (0.46) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL3930248 | 0.82 | DPP4 (0.46) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL2059099 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL1770627 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL1685517 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL20902879 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL13482942 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9DPP7IARS1 | |
| SCHEMBL76741 | 0.80 | DPP4 (0.44) | DPP4DPP8DPP9DPP7IARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1121366-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 2001-08-08 | — | — | EP | disclosed |
| WO-1999051613-A1 | PRODRUGS OF PHOSPHOROUS-CONTAINING PHARMACEUTICALS | MEDIVIR AB (SE) | 1999-10-14 | — | — | WO | disclosed |