Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL677360 | 0.98 | TDP1 (0.44) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| SCHEMBL7865332 | 0.84 | TDP1 (0.38) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| Lithium Ion SCHEMBL6850337 | 0.81 | TDP1 (0.40) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| SCHEMBL6850429 | 0.80 | PTPN1 (0.39) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| SCHEMBL14838145 | 0.79 | TDP1 (0.62) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| SCHEMBL14397681 | 0.79 | TDP1 (0.34) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| SCHEMBL13996068 | 0.78 | MEN1 (0.41) | ALDH1A1 | |
| SCHEMBL7039707 | 0.78 | PTPN1 (0.40) | TDP1HDAC1HDAC8ALDH1A1CA12 | |
| SCHEMBL683397 | 0.77 | TDP1 (0.42) | TDP1ALDH1A1CA1CA2CA9 | |
| SCHEMBL6129791 | 0.77 | CA2 (0.40) | HDAC1HDAC8CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095071-A1 | AROMATIC POLYMERS WITH PENDANT FLUORINATED IONIC GROUPS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2001-05-02 | — | — | EP | disclosed |
| WO-1999067304-A1 | AROMATIC POLYMERS WITH PENDANT FLUORINATED IONIC GROUPS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1999-12-29 | — | — | WO | disclosed |