SCHEMBL7865394

SCHEMBL7865394

COc1ccc(CC=C2CCCCN2)cc1

nearest known ligand 0.49

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
TP53 P04637 1/20 0.46
CYP3A4 P08684 1/20 0.46
ALOX15 P16050 1/20 0.46
TSHR P16473 1/20 0.46
ALOX12 P18054 1/20 0.46
HSD17B10 Q99714 1/20 0.40
IDO1 P14902 2/20 0.38
USP2 O75604 1/20 0.38
HRH3 Q9Y5N1 1/20 0.37
CYP1A2 P05177 1/20 0.36
PTGIR P43119 2/20 0.36
AGXT P21549 1/20 0.36
LTA4H P09960 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1887801 0.81 CYP1A2 (0.49) ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL1887799 0.81 CYP1A2 (0.49) ALDH1A1SMN1; SMN2CYP1A2
SCHEMBL7862815 0.79 ALDH1A1 (0.44) ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15
SCHEMBL1889060 0.70 EGFR (0.50) ALDH1A1
SCHEMBL1889059 0.70 EGFR (0.50) ALDH1A1
SCHEMBL28180903 0.69 ALDH1A1 (0.54) ALDH1A1SMN1; SMN2CYP3A4TSHRHSD17B10
SCHEMBL7333678 0.68 MIF (0.41) ALDH1A1SMN1; SMN2HSD17B10IDO1
SCHEMBL11437812 0.67 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15
SCHEMBL244069 0.67 ALDH1A1 (0.68) ALDH1A1SMN1; SMN2TP53CYP3A4ALOX15
SCHEMBL7621473 0.67 C3AR1 (0.42) TSHRHSD17B10HRH3TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001002417-A1 NUCLEOTIDE MONOMER CONTAINING SIX-MEMBERED AZARSUGAR AND ANTISENSE OLIGOMERS THEREOF DONGBU HANNONG CHEMICAL CO., LTD. (KR) 2001-01-11 WO disclosed