Octane

Octane

SCHEMBL7865572

CCCCCCCC.CCOC=O.NC(O)=S.NC(O)=S

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
FAAH O00519 1/20 0.37
TP53 P04637 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C19 P33261 1/20 0.37
SOAT1 P35610 1/20 0.37
TSHR P16473 5/20 0.37
GPR84 Q9NQS5 7/20 0.35
PPARG P37231 7/20 0.35
PPARD Q03181 7/20 0.35
PPARA Q07869 7/20 0.35
HDAC11 Q96DB2 5/20 0.35
PTPN1 P18031 3/20 0.35
ALDH1A1 P00352 2/20 0.35
TLR2 O60603 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
FABP4 P15090 2/20 0.35
SLC22A6 Q4U2R8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hexane SCHEMBL4881617 0.98 MEN1 (0.34) MEN1KMT2AFAAHTP53CYP1A2
Ethoxycarbonyl Group SCHEMBL4428871 0.90 ALOX15 (0.32) ALOX15
Ethoxycarbonyl Group SCHEMBL11691061 0.89 ALOX15 (0.35) ALDH1A1ALOX15
Ethoxycarbonyl Group SCHEMBL4879176 0.87 ALOX15 (0.33) ALOX15
Ethoxycarbonyl Group SCHEMBL4877557 0.87 ALOX15 (0.33) ALOX15
Hexyl Formate SCHEMBL4879088 0.86 CA1 (0.41)
Benzene SCHEMBL4437867 0.85 ALOX15 (0.32) ALOX15
Heptane SCHEMBL25434047 0.85 TSHR (0.48) FAAHTSHRALDH1A1EPHX1ADH1B
Nonane SCHEMBL27721173 0.85 TSHR (0.48) FAAHTSHRALDH1A1EPHX1ADH1B
Octane SCHEMBL27662967 0.85 TSHR (0.48) FAAHTSHRALDH1A1EPHX1ADH1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6315925-B1 USED AS ADDITIVE FOR STABILISING ORGANIC PRODUCTS THAT ARE SUBJECTED TO OXIDATIVE, THERMAL AND/OR LIGHT-INDUCED DEGRADATION CIBA SPECIALTY CHEMICALS CORPORATION 2001-11-13 US disclosed
US-5672574-A Stabilizers for organic materials CIBA-GEIGY CORPORATION (US) 1997-09-30 US disclosed