SCHEMBL7865615

SCHEMBL7865615

N#CSc1cc(OCP(=O)(O)O)c2nc([AsH2])sc2c1C1CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FBP1 P09467 4/20 0.31
NOTUM Q6P988 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4135222 0.88 FBP1 (0.36) FBP1NOTUM
Bromide SCHEMBL4134443 0.87 FBP1 (0.36) FBP1
Bromide SCHEMBL4134438 0.87 FBP1 (0.35) FBP1
SCHEMBL4120720 0.71 FBP1 (0.37) FBP1
SCHEMBL4893473 0.71 FBP1 (0.36) FBP1
SCHEMBL4123475 0.71 FBP1 (0.36) FBP1
SCHEMBL4129085 0.70 FBP1 (0.35) FBP1
SCHEMBL4134607 0.69 FBP1 (0.40) FBP1
SCHEMBL4133694 0.69 FBP1 (0.38) FBP1
SCHEMBL4129132 0.68 FBP1 (0.34) FBP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1112275-A1 NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE Metabasis Therapeutics, Inc. (US) 2001-07-04 EP disclosed
WO-2000014095-A1 NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE METABASIS THERAPEUTICS, INC. (US) 2000-03-16 WO disclosed