Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6819178 | 0.80 | NAMPT (0.57) | ALDH1A1LMNANAMPTMAPTABL1 | |
| SCHEMBL6815242 | 0.79 | ALDH1A1 (0.65) | ALDH1A1L3MBTL1LMNASMN1; SMN2NPC1 | |
| SCHEMBL7081264 | 0.76 | MEN1 (0.69) | ALDH1A1L3MBTL1LMNASMN1; SMN2NPC1 | |
| SCHEMBL9081119 | 0.75 | SMN1; SMN2 (0.66) | ALDH1A1LMNASMN1; SMN2RAB9AKDM4E | |
| SCHEMBL30640559 | 0.71 | GRM5 (0.53) | LMNASMN1; SMN2NPC1RAB9AKDM4E | |
| SCHEMBL3995125 | 0.70 | ALDH1A1 (0.68) | ALDH1A1L3MBTL1LMNASMN1; SMN2NPC1 | |
| SCHEMBL24730061 | 0.70 | ATR (0.47) | ALDH1A1SMN1; SMN2KDM4ENAMPTMAPT | |
| SCHEMBL30641926 | 0.70 | ATR (0.47) | ALDH1A1SMN1; SMN2KDM4ENAMPTMAPT | |
| SCHEMBL7078740 | 0.69 | MAPT (0.73) | ALDH1A1L3MBTL1LMNASMN1; SMN2NPC1 | |
| SCHEMBL38657047 | 0.68 | MAP4K4 (0.49) | ALDH1A1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140913-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000034269-A1 | THIOUREA INHIBITORS OF HERPES VIRUSES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-06-15 | — | — | WO | disclosed |