Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.48 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.48 |
| ▸ | PSMD12 | O00232 | 1/20 | 0.48 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.48 |
| ▸ | PSMD3 | O43242 | 1/20 | 0.48 |
| ▸ | PSMC3 | P17980 | 1/20 | 0.48 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.48 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.48 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.48 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.48 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5917532 | 0.84 | SMN1; SMN2 (0.58) | NQO2ALDH1A1HSD17B10MAPTPOLB | |
| SCHEMBL28741245 | 0.80 | CNR1 (0.42) | ALDH1A1MEN1KMT2ASYK | |
| SCHEMBL3135779 | 0.76 | SYK (0.46) | KMT2ASYK | |
| SCHEMBL592446 | 0.76 | NQO2 (0.66) | NQO2ALDH1A1CYP1A2HSD17B10MAPT | |
| SCHEMBL694904 | 0.75 | NQO2 (0.56) | NQO2ALDH1A1CYP1A2HSD17B10MAPT | |
| SCHEMBL3786463 | 0.74 | NQO2 (0.73) | NQO2ALDH1A1CYP1A2HSD17B10MAPT | |
| SCHEMBL14384393 | 0.73 | NQO2 (0.76) | NQO2ALDH1A1CYP1A2HSD17B10MAPT | |
| SCHEMBL5016071 | 0.73 | NQO2 (0.76) | NQO2ALDH1A1CYP1A2HSD17B10MAPT | |
| SCHEMBL1901172 | 0.73 | ALDH1A1 (0.76) | ALDH1A1CYP1A2HSD17B10MAPTPOLB | |
| SCHEMBL731180 | 0.73 | NQO2 (0.54) | NQO2ALDH1A1CYP1A2HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1161438-A1 | 6-O-SUBSTITUTED MACROLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 2001-12-12 | — | — | EP | claimed |
| WO-2000055168-A1 | 6-O-SUBSTITUTED MACROLIDES HAVING ANTIBACTERIAL ACTIVITY | ABBOTT LABORATORIES (US) | 2000-09-21 | — | — | WO | claimed |