Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 4/20 | 0.40 |
| ▸ | HTR2B | P41595 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | PNMT | P11086 | 1/20 | 0.35 |
| ▸ | CD44 | P16070 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047642 | 1.00 | MEN1 (0.51) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL8037851 | 0.92 | MEN1 (0.45) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL3694587 | 0.81 | HTR2C (0.60) | HTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL25412282 | 0.77 | HTR2A (0.47) | HTR2AHTR2CHTR2BPNMT | |
| SCHEMBL23854676 | 0.76 | MEN1 (0.33) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL11007168 | 0.75 | CYP3A4 (0.42) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL3922304 | 0.75 | MEN1 (0.56) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL329626 | 0.75 | HTR2C (0.67) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL329949 | 0.75 | HTR2C (0.67) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL31159134 | 0.75 | HTR2C (0.67) | MEN1CYP3A4CYP2D6KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290334-A | Preparation method of Lifeiste key intermediate | 上海医药工业研究院有限公司 | 2024-07-05 | — | — | CN | disclosed |
| US-6300316-B1 | ANTIBIOTICS AS BACTERICIDE | PFIZER INC | 2001-10-09 | — | — | US | disclosed |
| US-6025350-A | C-4\" substituted macrolide antibiotics | PFIZER INC. (US) | 2000-02-15 | — | — | US | disclosed |
| EP-0895999-A1 | C-4\" substituted macrolide antibiotics | Pfizer Products Inc. (US) | 1999-02-10 | — | — | EP | disclosed |
| US-4760145-A | Certain 6,7-methylene dioxydihydro or tetrahydro-isoquinoline derivatives | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0214905-A2 | Tetrahydroisoquinoline derivatives | MITSUBISHI KASEI CORPORATION (JP) | 1987-03-18 | — | — | EP | disclosed |