Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.35 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 3/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31047642 | 0.92 | MEN1 (0.51) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL7865801 | 0.92 | MEN1 (0.51) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| Hydrochloric Acid SCHEMBL3694587 | 0.74 | HTR2C (0.60) | HTR2AHTR2CHTR2BIDO1 | |
| SCHEMBL25412282 | 0.71 | HTR2A (0.47) | HTR2AHTR2CHTR2B | |
| SCHEMBL7842721 | 0.71 | MEN1 (0.47) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL23854676 | 0.70 | MEN1 (0.33) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL3702121 | 0.69 | CYP2D6 (0.45) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL11007168 | 0.69 | CYP3A4 (0.42) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL329626 | 0.69 | HTR2C (0.67) | MEN1CYP3A4CYP2D6KMT2AHTR2A | |
| SCHEMBL3922304 | 0.69 | MEN1 (0.56) | MEN1CYP3A4CYP2D6KMT2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025350-A | C-4\" substituted macrolide antibiotics | PFIZER INC. (US) | 2000-02-15 | — | — | US | disclosed |