SCHEMBL7865822

SCHEMBL7865822

CC(C)C(C)NC(=O)c1cc(Cl)cc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GRN P28799 9/20 0.57
SORT1 Q99523 9/20 0.57
GPR139 Q6DWJ6 1/20 0.46
CNR1 P21554 1/20 0.44
CNR2 P34972 1/20 0.44
ATM Q13315 1/20 0.44
TPMT P51580 1/20 0.43
RAB9A P51151 1/20 0.43
HPGD P15428 1/20 0.42
FLT1 P17948 1/20 0.41
FLT4 P35916 1/20 0.41
KDR P35968 1/20 0.41
FABP4 P15090 1/20 0.41
CCKBR P32239 1/20 0.41
KCNH2 Q12809 1/20 0.41
CACNA1I Q9P0X4 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2909101 0.86 TAS1R3 (0.47) GRNSORT1
SCHEMBL1829148 0.84 GRN (0.60) GRNSORT1GPR139TPMTRAB9A
SCHEMBL13753410 0.82 HPGD (0.62) GPR139ATMRAB9AHPGDKCNH2
SCHEMBL23213655 0.79 GRN (0.64) GRNSORT1GPR139TPMTFABP4
SCHEMBL31360685 0.79 GRN (0.64) GRNSORT1GPR139TPMTFABP4
SCHEMBL23213654 0.79 GRN (0.64) GRNSORT1GPR139TPMTFABP4
SCHEMBL8802498 0.78 GRN (0.54) GRNSORT1GPR139TPMTRAB9A
SCHEMBL24571660 0.77 TAS1R3 (0.49) HPGD
SCHEMBL29263789 0.77 TAS1R3 (0.41) GRNSORT1
SCHEMBL13754407 0.77 GRN (0.60) GRNSORT1GPR139RAB9AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0851790-B1 THE APPLICATION OF DRY SPREADABLE WATER DISPERSIBLE GRANULE COMPOSITIONS RHODIA (US) 2001-12-05 EP disclosed
US-5759943-A CHARCOAL, SURFACTANT MIXTURE RHONE-POULENC INC. (US) 1998-06-02 US disclosed
US-5738623-A DEACTIVATING TOXIC PESICIDAL BIOACTIVITY BY SPREADING A GRANULAR MIXTURE OF ALKYLNAPHTHALENESULFONATE, ACTIVATED CHARCOAL, ALKYLNAPHTHALENESULFONATE-FORMALDEHYDE CONDENSATE, TRISTYRYLPHENOL ETHOXYLATE, CONTACTING WITH WATER AQUATROLS CORPORATION OF AMERICA, INC. (US) 1998-04-14 US disclosed
US-4405360-A Controlled release of herbicide compounds utilizing a thermoplastic matrix ENVIRONMENTAL CHEMICALS, INC. (US) 1983-09-20 US disclosed
US-4360375-A Phenoxyphenoxy unsaturated derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1982-11-23 US disclosed
US-4263040-A Phenoxyphenoxy unsaturated derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1981-04-21 US disclosed
US-4163661-A Phenoxyphenoxy crotonic acid derivatives and herbicidal composition KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) 1979-08-07 US disclosed