SCHEMBL7866064

SCHEMBL7866064

O=C1CCC(Cc2ccccc2O)CC1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.49
POLB P06746 1/20 0.49
HSPA5 P11021 1/20 0.42
AKR1B1 P15121 1/20 0.41
MPO P05164 1/20 0.39
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38
HIF1A Q16665 1/20 0.38
ESR2 Q92731 1/20 0.38
TAAR1 Q96RJ0 1/20 0.37
TACR1 P25103 2/20 0.36
IDO1 P14902 2/20 0.36
CA12 O43570 1/20 0.36
CA2 P00918 1/20 0.36
HRH3 Q9Y5N1 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2051705 0.85 HSPA5 (0.52) ALDH1A1POLBHSPA5AKR1B1MPO
SCHEMBL386760 0.79 HSPA5 (0.46) ALDH1A1POLBHSPA5AKR1B1MPO
SCHEMBL18726535 0.79 HSPA5 (0.46) ALDH1A1POLBHSPA5AKR1B1MPO
SCHEMBL8631879 0.79 ALDH1A1 (0.45) ALDH1A1CYP2D6TSHRTAAR1IDO1
SCHEMBL2389281 0.76 SLC6A4 (0.58) ALDH1A1POLBHSPA5MPOCYP2D6
SCHEMBL4223375 0.76 AR (0.41) ALDH1A1CYP2D6TSHRHIF1ATACR1
SCHEMBL6402700 0.73 HRH3 (0.41) ALDH1A1POLBHSPA5AKR1B1MPO
SCHEMBL5675291 0.73 GBA1 (0.57) ALDH1A1
Bicarbonate SCHEMBL2854194 0.73 GBA1 (0.52)
SCHEMBL6403702 0.72 ALDH1A1 (0.43) ALDH1A1POLBHSPA5TAAR1HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6313351-B1 Process for producing alicyclic monoketones and process for producing alicyclic diketones HONSHU CHEMICAL INDUSTRY CO., LTD. (JP) 2001-11-06 US disclosed