SCHEMBL7866086

SCHEMBL7866086

NCCC[C@]1(n2ccc(=O)[nH]c2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.40
SLC28A2 O43868 1/20 0.40
SLC29A1 Q99808 1/20 0.40
SLC28A3 Q9HAS3 1/20 0.40
P2RY6 Q15077 8/20 0.36
P2RY14 Q15391 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
DUT P33316 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27879786 0.91 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL29101322 0.89 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL9670017 0.87 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL10697841 0.87 SLC28A1 (0.41) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2242410 0.86 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL516166 0.84 SLC28A1 (0.43) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL95904 0.83 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2009955 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL8099831 0.81 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL15285199 0.80 SLC28A1 (0.40) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6312953-B1 MODIFIED OLIGONUCLEOTIDE COMPLEMENTARY TO A TARGET SEQUENCE AND HAVING AT LEAST TWO CROSSLINKING AGENTS COVALENTLY ATTATCHED; GENE EXPRESSION INHIBITION; DNA SEQUENCING; GENETIC MAPPING EPOCH PHARMACEUTICALS, INC. 2001-11-06 US disclosed