SCHEMBL2009955

SCHEMBL2009955

N[C@]1(n2ccc(=O)[nH]c2=O)C[C@H](O)[C@@H](CO)O1

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
SLC28A1 O00337 1/20 0.44
SLC28A2 O43868 1/20 0.44
SLC29A1 Q99808 1/20 0.44
SLC28A3 Q9HAS3 1/20 0.44
P2RY6 Q15077 8/20 0.39
P2RY14 Q15391 1/20 0.34
DUT P33316 2/20 0.33
CRBN Q96SW2 1/20 0.33
P2RY2 P41231 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL51723 0.84 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL28786348 0.84 SLC28A1 (0.45) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27451524 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL2242410 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL249822 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL27703606 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL65485 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL414705 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
Hydrochloric Acid SCHEMBL27782735 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6
SCHEMBL438241 0.82 SLC28A1 (0.44) SLC28A1SLC28A2SLC29A1SLC28A3P2RY6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114126668-A Compositions and methods for the treatment of hemochromatosis 超基因制药股份有限公司 2022-03-01 CN claimed
EP-1493818-A2 Nucleoside triphosphates and their incorporation into ribozymes RIBOZYME PHARMACEUTICALS, INC. (US) 2005-01-05 EP claimed
US-6509460-B1 Contacting the modified nucleotide triphosphate with a mixture comprising a nucleic acid template, an RNA polymerase enzyme, and an enhancer of modified nucleotide triphosphate incorporation RIBOZYME PHARMACEUTICALS, INC. 2003-01-21 US claimed
US-6127535-A FOR THE INCORPORATION OF MODIFIED (NON-STANDARD) AND UNMODIFIED NUCLEOTIDES INTO NUCLEIC ACIDS RIBOZYME PHARMACEUTICALS, INC. (US) 2000-10-03 US claimed
EP-4713450-A1 ENGINEERED CONSTRUCTS WITH CASSETTE ARRANGEMENTS FOR INCREASED TRANSCRIPTION OF RNA PAYLOADS Shape Therapeutics Inc. (US) 2026-03-25 EP disclosed
EP-4580609-A2 COMPOSITIONS AND METHODS FOR DELIVERY OF RNA Rejuvenation Technologies Inc. (US) 2025-07-09 EP disclosed
CN-119789852-A Compositions and methods for delivering RNA 再生技术有限责任公司 2025-04-08 CN disclosed
WO-2025049632-A1 COMPOSITIONS AND METHODS FOR BROAD DELIVERY OF RNA TO TISSUE REJUVENATION TECHNOLOGIES INC. (US) 2025-03-06 WO disclosed
CN-119317714-A Nucleic acid modified biological cells with amplification-dependent gene expression 蒂宾根大学医学院 2025-01-14 CN disclosed
EP-4479406-A1 OXAZINE DYES AND THEIR USE IN NUCLEIC ACID AMPLIFICATION REACTIONS Promega Corporation (US) 2024-12-25 EP disclosed
CN-112805386-B Plasmid containing a sequence encoding mRNA having a segmented poly (A) tail 埃泽瑞斯公司 2024-12-03 CN disclosed
WO-2024238584-A1 ENGINEERED CONSTRUCTS WITH CASSETTE ARRANGEMENTS FOR INCREASED TRANSCRIPTION OF RNA PAYLOADS SHAPE THERAPEUTICS INC. (US) 2024-11-21 WO disclosed
WO-2011069587-A1 LYOPHILIZATION OF NUCLEIC ACIDS IN LACTATE-CONTAINING SOLUTIONS CUREVAC GMBH (DE) 2011-06-16 WO disclosed
WO-2007016455-A2 COMPOSITIONS AND METHODS USING AMINOGLYCOSIDES TO BIND DNA AND RNA CLEMSON UNIVERSITY RESEARCH FOUNDATION (US) 2007-02-08 WO disclosed
EP-1212416-A2 NUCLEIC ACID BASED MODULATORS OF GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2002-06-12 EP disclosed
WO-2001016312-A2 NUCLEIC ACID BASED MODULATORS OF GENE EXPRESSION RIBOZYME PHARMACEUTICALS, INC. (US) 2001-03-08 WO disclosed
EP-1073732-A2 NUCLEOSIDE TRIPHOSPHATES AND THEIR INCORPORATION INTO RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 2001-02-07 EP disclosed
WO-1999055857-A2 NUCLEOSIDE TRIPHOSPHATES AND THEIR INCORPORATION INTO RIBOZYMES RIBOZYME PHARMACEUTICALS, INC. (US) 1999-11-04 WO disclosed
US-5902879-A Methoxyoxalamido and succinimido precursors for nucleophilic addition to nucleosides, nucleotides and oligonucleotides FIDELITY SYSTEMS, INC. (US) 1999-05-11 US disclosed
WO-1998050530-A9 ENZYMATIC NUCLEIC ACIDS: SYNTHESIS, SELECTION AND USE RIBOZYME PHARM INC (US) 1999-03-25 WO disclosed