Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRND | Q07001 | 6/20 | 0.56 |
| ▸ | CHRNA1 | P02708 | 2/20 | 0.56 |
| ▸ | CHRNG | P07510 | 2/20 | 0.56 |
| ▸ | CHRNB1 | P11230 | 2/20 | 0.56 |
| ▸ | GRIA1 | P42261 | 5/20 | 0.52 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7866090 | 1.00 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL24122752 | 1.00 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL29735603 | 0.96 | CHRND (0.56) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30471344 | 0.93 | NPY4R (0.55) | CHRND | |
| SCHEMBL7867780 | 0.92 | NPY4R (0.58) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL7867793 | 0.92 | NPY4R (0.58) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL26179142 | 0.92 | CHRND (0.54) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL30138974 | 0.91 | CALCRL (0.55) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 | |
| SCHEMBL29479574 | 0.91 | OPRD1 (0.51) | CHRNDCHRNA1CHRNGCHRNB1 | |
| SCHEMBL7122844 | 0.89 | SLC15A2 (0.59) | CHRNDCHRNA1CHRNGCHRNB1GRIA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303116-B1 | CAPABLE OF TRANSDUCING THERAPEUTIC GENES INTO NON-DIVIDING CELLS. | THOMAS JEFFERSON UNIVERSITY | 2001-10-16 | — | — | US | disclosed |