Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.41 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 4/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LPAR2 | Q9HBW0 | 4/20 | 0.33 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.33 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26724993 | 0.83 | PAOX (0.43) | SPHK1SPHK2USP2HTTPLA2G2C | |
| SCHEMBL10119365 | 0.83 | SPHK1 (0.44) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL31086433 | 0.83 | SPHK1 (0.44) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL7863942 | 0.81 | PTPN1 (0.35) | SPHK1HTTPLA2G2CALDH1A1CES2 | |
| SCHEMBL26724992 | 0.81 | PAOX (0.40) | SPHK1SPHK2USP2PLA2G2CALDH1A1 | |
| SCHEMBL11858528 | 0.81 | SPHK1 (0.42) | SPHK1SPHK2USP2HTTLPAR5 | |
| SCHEMBL10599228 | 0.79 | ALDH1A1 (0.55) | PLA2G2CALDH1A1HSD17B10 | |
| SCHEMBL10596601 | 0.79 | ALDH1A1 (0.55) | PLA2G2CALDH1A1HSD17B10 | |
| SCHEMBL2090432 | 0.79 | SPHK1 (0.42) | SPHK1SPHK2USP2HTTPLA2G2C | |
| SCHEMBL7863608 | 0.78 | PTPN1 (0.36) | HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0623608-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LTD (JP) | 2001-05-30 | — | — | EP | disclosed |
| EP-0632031-B1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 2000-05-03 | — | — | EP | disclosed |
| EP-0546177-B1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LTD (JP) | 1998-01-07 | — | — | EP | disclosed |
| US-5574061-A | ANTILIPEMIC AGENT, ANTIATHEROSCLEROSIS, ACAT INHIBITOR | TEIJIN LIMITED (JP) | 1996-11-12 | — | — | US | disclosed |
| US-5496853-A | FOR TREATING HYPERCHOLESTEROLEMIA | TEIJIN LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| EP-0632031-A1 | CONDENSED BENZOXA RING COMPOUND, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1995-01-04 | — | — | EP | disclosed |
| EP-0623608-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL PREPARATION CONTAINING THE SAME AS ACTIVE INGREDIENT | TEIJIN LIMITED (JP) | 1994-11-09 | — | — | EP | disclosed |
| EP-0546177-A1 | BENZOPYRAN DERIVATIVE, PRODUCTION THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | TEIJIN LIMITED (JP) | 1993-06-16 | — | — | EP | disclosed |