SCHEMBL78662

SCHEMBL78662

O=C1c2ccccc2-c2cc(O)c3c4c(O)cc5c6c(ccc(c7ccc1c2c73)c64)C(=O)c1ccccc1-5

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 7/20 0.55
MCL1 Q07820 7/20 0.55
MAPK1 P28482 4/20 0.54
CYP1A2 P05177 2/20 0.54
HIF1A Q16665 2/20 0.54
GNG2 P59768 1/20 0.54
GNB1 P62873 1/20 0.54
MAPT P10636 6/20 0.44
KDM4E B2RXH2 3/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
PABPC1 P11940 2/20 0.44
MEN1 O00255 6/20 0.43
KMT2A Q03164 6/20 0.43
MAOA P21397 3/20 0.43
CYP3A4 P08684 2/20 0.43
ALDH1A1 P00352 2/20 0.43
APEX1 P27695 2/20 0.43
HSD17B10 Q99714 2/20 0.43
RECQL P46063 2/20 0.43
HPGD P15428 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78583 0.93 BCL2 (0.55) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL11089683 0.85 MAPK1 (0.43) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL27636780 0.83 MAPK1 (0.54) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL4410143 0.82 MAPT (0.53) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL21110889 0.79 MAPK1 (0.50) BCL2MCL1MAPK1CYP1A2HIF1A
Anthraquinone SCHEMBL4307959 0.79 BCL2 (0.60) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL12031457 0.79 BCL2 (0.60) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL12449237 0.79 BCL2 (0.60) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL29356917 0.79 BCL2 (0.60) BCL2MCL1MAPK1CYP1A2HIF1A
SCHEMBL88058 0.79 BCL2 (0.60) BCL2MCL1MAPK1CYP1A2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104725209-A Preparation method of 16,17-dihydroxy dibenzanthrone TIANCHANG TIANJIA CHEMICAL TECHNOLOGY CO LTD 2015-06-24 CN claimed
EP-0308842-B1 PROCESS FOR THE PREPARATION OF ALCOXY (ISO)-VIOLANTHRENEDIONE BASF Aktiengesellschaft (DE) 1992-12-23 EP claimed
EP-0259849-B1 PROCESS FOR THE PREPARATION OF C.I. VAT BLUE 16 BASF Aktiengesellschaft (DE) 1991-10-16 EP claimed
US-4882095-A Preparation of alkoxy(iso)violanthrenediones BASF AKTIENGESELLSCHAFT (DE) 1989-11-21 US claimed
US-4824608-A ALKYLATING 16,17-DIHYDROXYVIOLANTHRENE-5,10-DIONE IN TERTIARY ALIPHATIC OR CYCLOALIPHATIC AMINE AS SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1989-04-25 US claimed
EP-2095131-B1 TAGGED PETROLEUM PRODUCTS AND METHODS OF DETECTING THE SAME AUTHENTIX INC (US) 2018-05-02 EP disclosed
CN-104725209-A Preparation method of 16,17-dihydroxy dibenzanthrone TIANCHANG TIANJIA CHEMICAL TECHNOLOGY CO LTD 2015-06-24 CN disclosed
CN-103804163-A Method for preparing 16,17-dialkoxyviolanthrone derivatives UNIV BEIJING CHEMICAL 2014-05-21 CN disclosed
US-8129190-B2 Via violanthrone compounds APPLIED NANOTECH HOLDINGS, INC. (US) 2012-03-06 US disclosed
CN-101270064-B Violanthrone analogue and uses thereof UNIV EAST CHINA SCIENCE & TECH 2012-02-29 CN disclosed
EP-2095131-A1 TAGGED PETROLEUM PRODUCTS AND METHODS OF DETECTING THE SAME Authentix, Inc. (US) 2009-09-02 EP disclosed
CN-101270064-A Violanthrone analogue and uses thereof UNIV EAST CHINA SCIENCE & TECH (CN) 2008-09-24 CN disclosed
US-4882095-A Preparation of alkoxy(iso)violanthrenediones BASF AKTIENGESELLSCHAFT (DE) 1989-11-21 US disclosed
US-4824608-A ALKYLATING 16,17-DIHYDROXYVIOLANTHRENE-5,10-DIONE IN TERTIARY ALIPHATIC OR CYCLOALIPHATIC AMINE AS SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1989-04-25 US disclosed
US-4824608-A ALKYLATING 16,17-DIHYDROXYVIOLANTHRENE-5,10-DIONE IN TERTIARY ALIPHATIC OR CYCLOALIPHATIC AMINE AS SOLVENT BASF AKTIENGESELLSCHAFT (DE) 1989-04-25 US disclosed
EP-0073007-B1 METHOD FOR THE SQUARE DIMENSIONAL CONCENTRATION OF LIGHT, AND FLUORESCENT COMPOUNDS BASF Aktiengesellschaft (DE) 1984-12-27 EP disclosed
US-4486587-A LIGHFASTNESS, THEROMOSTABILITY BASF AKTIENGESELLSCHAFT (DE) 1984-12-04 US disclosed
EP-0073007-A1 Method for the square dimensional concentration of light, and fluorescent compounds BASF Aktiengesellschaft (DE) 1983-03-02 EP disclosed
EP-0061624-A1 Cationic dyes and their use BASF Aktiengesellschaft (DE) 1982-10-06 EP disclosed
US-4198529-A Process for the production of alkoxy-substituted polycyclic aromatic compounds CIBA-GEIGY CORPORATION (US) 1980-04-15 US disclosed