SCHEMBL11089683

SCHEMBL11089683

CC(C)Oc1cc2c3c(ccc4c5ccc6c7c(cc(O)c(c1c34)c75)-c1ccccc1C6=O)C(=O)c1ccccc1-2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.43
CYP1A2 P05177 1/20 0.43
GNG2 P59768 1/20 0.43
GNB1 P62873 1/20 0.43
HIF1A Q16665 1/20 0.43
BCL2 P10415 5/20 0.41
MCL1 Q07820 4/20 0.41
STK17B O94768 1/20 0.38
MAPT P10636 6/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
KDM4E B2RXH2 2/20 0.37
PABPC1 P11940 1/20 0.37
MEN1 O00255 5/20 0.35
KMT2A Q03164 5/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
APEX1 P27695 2/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA7 P43166 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78662 0.85 BCL2 (0.55) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL78583 0.79 BCL2 (0.55) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL3408840 0.78 CYP1A2 (0.50) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL30606662 0.78 CYP1A2 (0.50) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL29378901 0.78 CYP1A2 (0.50) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL9012650 0.73 PTPRC (0.49) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL31120783 0.73 PTPRC (0.49) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL11095238 0.72 CYP1A2 (0.44) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL13500629 0.72 CYP1A2 (0.42) MAPK1CYP1A2GNG2GNB1HIF1A
SCHEMBL22902140 0.70 PRMT1 (0.42) HIF1AMAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4486587-A LIGHFASTNESS, THEROMOSTABILITY BASF AKTIENGESELLSCHAFT (DE) 1984-12-04 US disclosed
EP-0073007-A1 Method for the square dimensional concentration of light, and fluorescent compounds BASF Aktiengesellschaft (DE) 1983-03-02 EP disclosed