SCHEMBL7866563

SCHEMBL7866563

Nc1cccc(Oc2ccc(-c3ccc(Oc4cccc(N)c4)c(Br)c3)cc2Br)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.52
MAPT P10636 2/20 0.46
POLB P06746 1/20 0.46
HSP90AA1 P07900 1/20 0.46
ALDH1A1 P00352 5/20 0.44
CYP3A4 P08684 3/20 0.44
TP53 P04637 1/20 0.41
GAA P10253 2/20 0.40
MEN1 O00255 1/20 0.40
MITF O75030 1/20 0.40
GFER P55789 1/20 0.40
KMT2A Q03164 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NLRP1 Q9C000 1/20 0.40
NOD2 Q9HC29 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.38
MAOA P21397 1/20 0.38
MAPK1 P28482 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7194405 0.89 MAOB (0.55) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL8914761 0.80 MAPT (0.50) MAOBMAPTPOLBALDH1A1CYP3A4
SCHEMBL7633144 0.79 MAOB (0.52) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL5604536 0.79 MAOB (0.52) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL5604820 0.79 MAPT (0.58) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL7195568 0.78 MAOB (0.59) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL16335497 0.77 EPAS1 (0.54) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL25135228 0.77 MAOB (0.58) MAOBMAPTPOLBHSP90AA1ALDH1A1
SCHEMBL5552580 0.77 MAOA (0.52) MAOBMAPTALDH1A1CYP3A4GAA
SCHEMBL7631900 0.76 MAOB (0.56) MAOBMAPTPOLBHSP90AA1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9735429-B2 Lithium ion secondary battery HITACHI, LTD. (JP) 2017-08-15 US disclosed
EP-2858150-B1 LITHIUM ION SECONDARY BATTERY HITACHI LTD (JP) 2017-03-15 EP disclosed
US-20160304716-A1 FRICTION AND WEAR RESISTANT ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2016-10-20 US disclosed
EP-2899233-A1 Chemical processing articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
EP-2899231-A1 Aerospace articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
EP-2899230-A1 Automotive articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
EP-2899232-A1 Oil and gas recovery articles Solvay Specialty Polymers USA, LLC. (US) 2015-07-29 EP disclosed
US-20150155563-A1 LITHIUM ION SECONDARY BATTERY HITACHI, LTD., (JP) 2015-06-04 US disclosed
WO-2015059216-A1 FRICTION AND WEAR RESISTANT ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2015-04-30 WO disclosed
EP-2858150-A1 LITHIUM ION SECONDARY BATTERY Hitachi, Ltd. (JP) 2015-04-08 EP disclosed
US-5043419-A Reacting an aromatic diamine, a tetracarboxylic dianhydride, and a dicarboxylic anhydride; molded products for air and space craft; heat resistant; mechanical strength MITSUI TOATSU CHEMICALS, INC. (JP) 1991-08-27 US disclosed
US-5041520-A Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-08-20 US disclosed
EP-0430640-A1 Polyimide based resin composition MITSUI TOATSU CHEMICALS, Inc. (JP) 1991-06-05 EP disclosed
US-5013817-A Monoamine reactant, melt processability MITSUI TOATSU CHEMICALS, INC. (JP) 1991-05-07 US disclosed
EP-0384712-A2 Carbon-fiber-reinforced polyimide resin compositions MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-08-29 EP disclosed
US-4937316-A Process for preparing polyimides AMDAHL CORPORATION (US) 1990-06-26 US disclosed
EP-0350203-A2 Process for preparing polyimide having excellent high temperature stability MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-01-10 EP disclosed
EP-0330505-A1 Process for preparing polyimides MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-30 EP disclosed
EP-0315479-A2 Process for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-05-10 EP disclosed
EP-0313407-A2 Method for preparing polyimide and composite material thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-26 EP disclosed