Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ASGR1 | P07306 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL503444 | 0.72 | CA14 (0.53) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL30420929 | 0.72 | CA14 (0.41) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL28378832 | 0.72 | HDAC6 (0.39) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL98924 | 0.71 | CHRNB2 (0.44) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL28584989 | 0.71 | CA14 (0.51) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL745378 | 0.71 | CA14 (0.51) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL13803945 | 0.70 | CA14 (0.36) | CA14HDAC6CA12CA1CA7 | |
| SCHEMBL9019266 | 0.69 | CA14 (0.39) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL22168191 | 0.69 | CA14 (0.42) | CA14HDAC6SSTR4CA12CA1 | |
| SCHEMBL2086024 | 0.69 | CA14 (0.39) | CA14HDAC6SSTR4CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1144396-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | Bayer Corporation (US) | 2001-10-17 | — | — | EP | disclosed |
| WO-2000042031-A2 | SUBSTITUTED 2-ARYLIMINO HETEROCYCLES AND COMPOSITIONS CONTAINING THEM, FOR USE AS PROGESTERONE RECEPTOR BINDING AGENTS | BAYER CORPORATION (US) | 2000-07-20 | — | — | WO | disclosed |