Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3738182 | 0.85 | TSHR (0.37) | TSHRHPGDTHRB | |
| SCHEMBL10888478 | 0.82 | TSHR (0.34) | TSHRHPGDTHRB | |
| SCHEMBL10889317 | 0.82 | TSHR (0.34) | TSHRHPGDTHRB | |
| SCHEMBL968774 | 0.81 | TSHR (0.36) | TSHRHPGDTHRB | |
| SCHEMBL970917 | 0.80 | TSHR (0.35) | TSHRHPGD | |
| SCHEMBL10659651 | 0.79 | TSHR (0.32) | TSHRTHRB | |
| SCHEMBL1603671 | 0.78 | TSHR (0.37) | TSHRHPGDTHRB | |
| SCHEMBL7866733 | 0.78 | TSHR (0.36) | TSHRTHRB | |
| SCHEMBL1931611 | 0.76 | TSHR (0.38) | TSHRHPGDTHRB | |
| SCHEMBL1902982 | 0.76 | TSHR (0.42) | TSHRHPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6307081-B1 | MACROMONOMER HAS ONE OR MORE SILICON-BONDED HYDROGEN ATOMS AT ONE MOLECULAR CHAIN TERMINAL, AND ONE OR MORE ALIPHATICALLY UNSATURATED SILICON-BONDED ORGANIC GROUPS AT THE OTHER MOLECULAR CHAIN TERMINAL. | DOW CORNING SILICONE COMPANY, LTD. (JP) | 2001-10-23 | — | — | US | disclosed |