Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1603671 | 0.89 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL1931611 | 0.87 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL15477580 | 0.86 | TSHR (0.38) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7866745 | 0.85 | TSHR (0.36) | TSHRHPGDTHRB | |
| SCHEMBL5838258 | 0.85 | TSHR (0.39) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL7865311 | 0.82 | TSHR (0.42) | TSHRHPGDTHRB | |
| SCHEMBL10430815 | 0.81 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3738193 | 0.81 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL3738205 | 0.81 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A | |
| SCHEMBL18918481 | 0.81 | TSHR (0.37) | TSHRHPGDALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110817889-B | Preparation method of toughened silica aerogel, toughened silica aerogel and application of toughened silica aerogel | 上海中南建筑材料有限公司 | 2021-07-20 | — | — | CN | claimed |
| CN-110817889-A | Preparation method of toughened silica aerogel, toughened silica aerogel and application of toughened silica aerogel | 福建六树网络科技有限公司 | 2020-02-21 | — | — | CN | claimed |
| US-20140050917-A1 | LAMINATES OF UV CURABLE ACRYLATES AND SILANE PRIMERS HAVING GOOD ADHESION TO SILICEOUS SURFACES | NANOFILM LTD. (US) | 2014-02-20 | — | — | US | claimed |
| EP-4610266-A1 | METHOD FOR PRODUCING ORGANOSILICON COMPOUND HAVING (METH)ACRYLOXY GROUP, AND ORGANOSILICON COMPOUND HAVING ACRYLOXY GROUP | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-09-03 | — | — | EP | disclosed |
| US-20250188224-A1 | METHOD FOR PRODUCING ONE-TERMINAL FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-TERMINAL FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-06-12 | — | — | US | disclosed |
| EP-4506393-A1 | METHOD FOR PRODUCING ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE AND ONE-END-FUNCTIONAL ORGANOPOLYSILOXANE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2025-02-12 | — | — | EP | disclosed |
| EP-4482888-A1 | POLYORGANOSILOXANE COPOLYMERS WITH ORGANIC POLYMERS | Wacker Chemie AG (DE) | 2025-01-01 | — | — | EP | disclosed |
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. | 2024-12-12 | — | — | US | disclosed |
| EP-4448536-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | GELEST, INC. (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118742592-A | Polymer with organic polymer organosiloxane copolymers | 瓦克化学股份公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-118401532-A | High-purity polysiloxane macromer and preparation method thereof | 盖列斯特有限公司 | 2024-07-26 | — | — | CN | disclosed |
| EP-0853093-A1 | Copolymers of polyorganosiloxane, polyisobutylene and alkyl acrylates or methacrylates | DOW CORNING CORPORATION (US) | 1998-07-15 | — | — | EP | disclosed |
| EP-0852239-A1 | Homopolymerization of acrylate or methacrylate endblocked polydiorganosiloxanes | DOW CORNING CORPORATION (US) | 1998-07-08 | — | — | EP | disclosed |
| US-5731379-A | Copolymers of polyorganosiloxane, polyisobutylene, and alkyl acrylates or methacrylates | DOW CORNING CORPORATION (US) | 1998-03-24 | — | — | US | disclosed |
| EP-0814111-A1 | Process for producing diorganopolysiloxane | Chisso Corporation (JP) | 1997-12-29 | — | — | EP | disclosed |
| US-5672671-A | ANIONIC LIVING POLYMERIZATION OF A MIXTURE OF CYCLIC SILOXANE AND A PREVIOUSLY ACETYLATED POLYSILOXANE(WHICH HAD TWO SILANOL END GROUPS) USING LITHIUM COMPOUND AS INITIATOR, FOR NARRAOW MOLECULAR WEIGHT DISTRIBUTION, FEW BY-PRODUCTS | CHISSO CORPORATION (JP) | 1997-09-30 | — | — | US | disclosed |
| US-5578380-A | Crosslinkable silarylene-siloxane copolymers | MINNESOTA MINING & MFG (US) | 1996-11-26 | — | — | US | disclosed |
| EP-0636163-A1 | CROSSLINKABLE SILARYLENE-SILOXANE COPOLYMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-02-01 | — | — | EP | disclosed |
| US-5346980-A | Crosslinkable silarylene-siloxane copolymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1994-09-13 | — | — | US | disclosed |
| WO-1993021278-A1 | CROSSLINKABLE SILARYLENE-SILOXANE COPOLYMERS | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240409563-A1 | HIGH PURITY POLYSILOXANE MACROMERS AND METHOD FOR MAKING THE SAME | SSRP1, RPLP2, RPLP1 | TSHR 1897/4885HPGD 3909/4885ALDH1A1 837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.