SCHEMBL7866768

SCHEMBL7866768

COc1cc2c(OC)cc1cc2OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.46
NQO1 P15559 1/20 0.42
PDE4A P27815 1/20 0.41
PDE4B Q07343 1/20 0.41
PDE4C Q08493 1/20 0.41
PDE4D Q08499 1/20 0.41
HPGD P15428 3/20 0.41
LMNA P02545 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MAPT P10636 4/20 0.38
CYP3A4 P08684 2/20 0.38
EHMT2 Q96KQ7 1/20 0.37
MAOA P21397 1/20 0.36
CA12 O43570 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA4 P22748 1/20 0.36
CA7 P43166 1/20 0.36
CA9 Q16790 1/20 0.36
CA14 Q9ULX7 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27751211 0.74 ALDH1A1 (0.50) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL11496731 0.74 ALDH1A1 (0.63) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL1711296 0.74 CYP3A4 (0.53) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL29368836 0.74 CYP3A4 (0.53) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL27765191 0.71 ALDH1A1 (0.60) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL2138144 0.71 ALDH1A1 (0.60) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL21830349 0.71 ALDH1A1 (0.41) ALDH1A1PDE4APDE4BPDE4CPDE4D
SCHEMBL11267308 0.68 ALDH1A1 (0.39) ALDH1A1NQO1PDE4APDE4BPDE4C
SCHEMBL17183188 0.67 CDK5 (0.42) ALDH1A1NQO1HPGDLMNASMN1; SMN2
SCHEMBL1128095 0.67 NQO1 (0.56) ALDH1A1NQO1HPGDLMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0672741-B1 Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 2001-10-17 EP disclosed
EP-0637621-B1 Polymeric fluorescent substance and organic electroluminescence devices using the same SUMITOMO CHEMICAL CO (JP) 2000-05-17 EP disclosed
US-5980781-A HAVING LIGHT EMITTING LAYER BETWEEN THE ELECTRODES CONSISTING OF ONE PAIR OF AN ANODE AND A CATHODE, AT LEAST ONE OF WHICH ELECTRODES IS TRANSPARENT OR SEMI-TRANSPARENT, WHEREIN SAID LIGHT EMITTING LAYER COMPRISES A POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-11-09 US disclosed
US-5759709-A Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-02 US disclosed
US-5589320-A Polymeric fluorescent substance and organic electroluminescence devices using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-12-31 US disclosed
US-5543079-A POLYARYLENE VINYLIDENES HAVING THREE DIFFERENT UNITS AND CONTAINING ETHER, SULFIDE OR ESTER GROUPS; SOLBUILITY; HIGH QUANTUM YIELD WITH LOW DRIVE VOLTAGE; ELECTRICAL THIN FILMS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-06 US disclosed
EP-0672741-A1 Polymeric fluorescent substance and organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-09-20 EP disclosed
EP-0637621-A1 Polymeric fluorescent substance and organic electroluminescence devices using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-02-08 EP disclosed