Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7554616 | 0.90 | GRM5 (0.42) | TYK2GRM5MAPTKDM4ENR1I2 | |
| SCHEMBL7554621 | 0.90 | GRM5 (0.42) | TYK2GRM5MAPTKDM4ENR1I2 | |
| SCHEMBL8140398 | 0.88 | GRM5 (0.41) | TYK2GRM5MAPTKDM4ENR1I2 | |
| SCHEMBL8140399 | 0.88 | GRM5 (0.41) | TYK2GRM5MAPTKDM4ENR1I2 | |
| SCHEMBL8754729 | 0.86 | PTGDR2 (0.35) | GRM5MAPTPTGDR2 | |
| SCHEMBL7552513 | 0.85 | TYK2 (0.38) | TYK2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL7552516 | 0.85 | TYK2 (0.38) | TYK2MAPTKDM4EALDH1A1GAA | |
| SCHEMBL8673741 | 0.84 | CACNA1B (0.40) | TYK2GRM5KDM4ENR1I2CACNA1B | |
| SCHEMBL8673739 | 0.84 | CACNA1B (0.40) | TYK2GRM5KDM4ENR1I2CACNA1B | |
| SCHEMBL8492233 | 0.82 | CES2 (0.50) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6323155-B1 | EXCELLENT LEVEL OF HERBICIDAL ACTIVITY TOGETHER WITH CROP TOLERANCE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 2001-11-27 | — | — | US | disclosed |
| EP-0674629-B1 | 4-BENZOYL ISOXAZOLES DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE POULENC AGRICULTURE (GB) | 1998-07-08 | — | — | EP | disclosed |