Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 2/20 | 0.71 |
| ▸ | FLT1 | P17948 | 17/20 | 0.71 |
| ▸ | KDR | P35968 | 17/20 | 0.71 |
| ▸ | FGFR1 | P11362 | 14/20 | 0.71 |
| ▸ | FLT4 | P35916 | 10/20 | 0.71 |
| ▸ | EPHB2 | P29323 | 1/20 | 0.71 |
| ▸ | EGFR | P00533 | 10/20 | 0.71 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3012896 | 0.84 | KDR (1.00) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL29365791 | 0.84 | KDR (1.00) | FLT1KDRFGFR1FLT4EPHB2 | |
| SCHEMBL2140901 | 0.83 | FLT1 (0.98) | EPHA2FLT1KDRFGFR1FLT4 | |
| Hydrochloric Acid SCHEMBL7867640 | 0.83 | KDR (0.98) | FLT1KDRFGFR1FLT4EPHB2 | |
| Hydrochloric Acid SCHEMBL30078372 | 0.83 | KDR (0.98) | FLT1KDRFGFR1FLT4EPHB2 | |
| Hydrochloric Acid SCHEMBL27218181 | 0.83 | FLT1 (1.00) | EPHA2FLT1KDRFGFR1FLT4 | |
| SCHEMBL7867197 | 0.82 | FLT1 (0.66) | EPHA2FLT1KDRFGFR1FLT4 | |
| SCHEMBL5433644 | 0.82 | FLT1 (0.83) | EPHA2FLT1KDRFGFR1FLT4 | |
| SCHEMBL7864646 | 0.82 | KDR (1.00) | EPHA2FLT1KDRFGFR1FLT4 | |
| SCHEMBL7864660 | 0.82 | FLT1 (0.84) | FLT1KDRFGFR1FLT4EPHB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0885198-B1 | 4-ANILINOQUINAZOLINE DERIVATIVES | ASTRAZENECA AB (SE) | 2001-12-19 | — | — | EP | claimed |