⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3016359 | 0.85 | — | — | |
| SCHEMBL5730528 | 0.79 | — | — | |
| SCHEMBL2139630 | 0.78 | — | — | |
| SCHEMBL1461493 | 0.78 | CA12 (0.36) | — | |
| Carbon Dioxide SCHEMBL7040864 | 0.74 | CHRM2 (0.36) | — | |
| SCHEMBL10257125 | 0.72 | CHRM2 (0.59) | — | |
| SCHEMBL5965358 | 0.72 | — | — | |
| SCHEMBL208227 | 0.71 | — | — | |
| SCHEMBL28265390 | 0.69 | CHRM2 (0.33) | — | |
| SCHEMBL7768564 | 0.69 | CHRM2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 300 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210361562-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | REVEN PHARMACEUTICALS INC. (US) | 2021-11-25 | — | — | US | claimed |
| US-9867849-B2 | Methods of treating or ameliorating skin conditions with a magnetic dipole stabilized solution | REVEN PHARMACEUTICALS, INC. (US) | 2018-01-16 | — | — | US | claimed |
| US-20170360696-A1 | COMPOSITIONS AND METHODS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES | REVEN PHARMACEUTICALS INC. (US) | 2017-12-21 | — | — | US | claimed |
| US-20170112872-A1 | METHODS OF TREATING OR AMELIORATING SKIN CONDITIONS WITH A MAGNETIC DIPOLE STABILIZED SOLUTION | REVEN PHARMACEUTICALS, INC. (US) | 2017-04-27 | — | — | US | claimed |
| EP-1487806-B1 | 4-ANILINO QUINAZOLINE DERIVATIVES AS ANTIPROLIFERATIVE AGENTS | ASTRAZENECA AB (SE) | 2010-07-07 | — | — | EP | claimed |
| US-20070225291-A1 | Substituted Pyrazinone Compounds for the Treatment of Inflammation | PFIZER INC. | 2007-09-27 | — | — | US | claimed |
| EP-1678164-B1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | PHARMACIA CORP (US) | 2007-04-11 | — | — | EP | claimed |
| EP-1678146-A1 | PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| EP-1678164-A1 | SUBSTITUTED PYRAZINONE COMPOUNDS FOR THE TREATMENT OF INFLAMMATION | Pharmacia Corporation (US) | 2006-07-12 | — | — | EP | claimed |
| US-20050197338-A1 | Substituted pyrazole urea compounds for the treatment of inflammation | PHARMACIA AND UPJOHN COMPANY LLC | 2005-09-08 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| US-5773445-A | FUNGICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1998-06-30 | — | — | US | claimed |
| EP-0333174-B1 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1996-05-08 | — | — | EP | claimed |
| US-5187156-A | D-Tryptophan- and Phenylalanine-containing tripeptides as tachykinin antagonists; asthma | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-16 | — | — | US | claimed |
| EP-0230347-B1 | MACROLIDE COMPOUNDS, THEIR PREPARATION AND USE | Sankyo Company Limited (JP) | 1991-05-15 | — | — | EP | claimed |
| US-4916128-A | Thiadiazinones | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-04-10 | — | — | US | claimed |
| US-4912090-A | Antiparasitic milbemycin and avermectin derivatives | SANKYO COMPANY LIMITED (JP) | 1990-03-27 | — | — | US | claimed |
| EP-0333174-A2 | Peptide compounds, processes for preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1989-09-20 | — | — | EP | claimed |
| EP-0230347-A1 | Macrolide compounds, their preparation and use | Sankyo Company Limited (JP) | 1987-07-29 | — | — | EP | claimed |