Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.32 |
| ▸ | METAP1 | P53582 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7867443 | 0.81 | PDCD1 (0.36) | — | |
| SCHEMBL7867448 | 0.79 | FNTA (0.35) | FNTAFNTB | |
| SCHEMBL7862377 | 0.74 | KDM4E (0.37) | — | |
| SCHEMBL7903666 | 0.72 | FNTA (0.40) | FNTAFNTB | |
| SCHEMBL7903657 | 0.72 | FNTA (0.40) | FNTAFNTB | |
| SCHEMBL7862384 | 0.72 | ALDH1A1 (0.38) | — | |
| SCHEMBL2944388 | 0.71 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL7897649 | 0.71 | FNTA (0.56) | FNTAFNTB | |
| SCHEMBL7869110 | 0.71 | — | — | |
| SCHEMBL7870208 | 0.69 | FNTA (0.51) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6310095-B1 | INHIBITING OR TREATING CANCER, TREATING INTIMAL HYPERPLASIA ASSOCIATED WITH RESTENOSIS AND ATHEROSCLEROSIS, INHIBITING POST-TRANSLATIONAL MODIFICATION OF ONCOGENIC RAS PROTEIN BY PROTEIN FARNESYLTRANSFERASE AND/OR GERANYLGERANYLTRANSFERASE | UNIVERSITY OF PITTSBURGH | 2001-10-30 | — | — | US | disclosed |