Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL614652 | 0.89 | SLC13A5 (0.57) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL614651 | 0.89 | SLC13A5 (0.57) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL3386585 | 0.89 | SLC13A5 (0.57) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL1237071 | 0.83 | ALOX5 (0.49) | SLC13A5ALDH1A1ALOX5 | |
| SCHEMBL9620289 | 0.82 | GAA (0.51) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL8666772 | 0.82 | GAA (0.51) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL11050995 | 0.81 | HDAC3 (0.48) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL6778470 | 0.81 | HDAC3 (0.48) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL28351862 | 0.80 | POLB (0.53) | KMT2ALMNAKDM4EMEN1CYP1A2 | |
| SCHEMBL8954730 | 0.79 | POLB (0.49) | KMT2ALMNAKDM4EMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0937036-B1 | SUBSTITUTED 4-BIPHENYL-4-HYDROXYBUTYRIC ACID DERIVATIVES AS MATRIX METALLOPROTEASE INHIBITORS | BAYER AG (US) | 2001-12-05 | — | — | EP | disclosed |