Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | MAPT | P10636 | 10/20 | 0.54 |
| ▸ | HPGD | P15428 | 9/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370784 | 0.90 | FDPS (0.49) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL30802598 | 0.88 | FDPS (0.71) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL31268362 | 0.88 | FDPS (0.71) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL16360861 | 0.88 | FDPS (0.71) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL30407414 | 0.85 | FDPS (0.58) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL5455295 | 0.83 | FDPS (0.63) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL13212085 | 0.83 | FDPS (0.58) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL482374 | 0.82 | FDPS (0.77) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL13230109 | 0.81 | FDPS (0.57) | FDPSLMNAALDH1A1MAPTHPGD | |
| SCHEMBL3431684 | 0.81 | FDPS (0.56) | FDPSLMNAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140924-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035915-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-22 | — | — | WO | disclosed |