Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | TNF | P01375 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876133 | 0.87 | NPSR1 (0.71) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7876188 | 0.84 | POLB (0.58) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7867583 | 0.80 | NPSR1 (0.58) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7876429 | 0.80 | NPSR1 (0.57) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7867590 | 0.79 | NPSR1 (0.71) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7872611 | 0.79 | NPSR1 (0.73) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL7867465 | 0.77 | NPSR1 (0.57) | NPSR1MAPTLMNASMN1; SMN2KMT2A | |
| SCHEMBL3884012 | 0.77 | ACE (0.55) | NPSR1MAPTLMNASMN1; SMN2ACE | |
| SCHEMBL10449482 | 0.76 | FPR2 (0.63) | SMN1; SMN2KMT2AACE | |
| SCHEMBL8412092 | 0.76 | FPR2 (0.63) | SMN1; SMN2KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0800505-B1 | NOVEL IMMUNOTHERAPEUTIC ARYL AMIDES | CELGENE CORP (US) | 2001-09-26 | — | — | EP | claimed |