Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 15/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.52 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7876654 | 0.92 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL7867784 | 0.88 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7867795 | 0.88 | PTGS2 (0.53) | PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL7876356 | 0.87 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7867791 | 0.86 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7876295 | 0.85 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL7867779 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1 | |
| SCHEMBL7874480 | 0.85 | PTGS2 (0.48) | PTGS2PTGS1 | |
| SCHEMBL9210069 | 0.85 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL7878979 | 0.84 | PTGS2 (0.59) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316485-B1 | INHIBITS ACTIVITY OF CYCLOOXYGENASE-2; FOR THERAPY AND PROPHYLAXIS OF INFLAMMATION, THROMBOSIS, RHEUMATOID ARTHRITIS, ALZHEIMER'S DISEASE; AS ANALGESIC | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-11-13 | — | — | US | disclosed |