Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.54 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15209066 | 0.80 | NQO1 (0.48) | PARP10PLA2G4BL3MBTL1ALDH1A1RAB9A | |
| SCHEMBL15189660 | 0.77 | MAOB (0.69) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL521489 | 0.73 | NR4A1 (0.72) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL7860414 | 0.73 | LMNA (0.51) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL339813 | 0.73 | LMNA (0.82) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL27367676 | 0.73 | LMNA (0.82) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL11603274 | 0.73 | NR4A2 (0.96) | MAOBNR4A2NR4A1NR4A3PARP10 | |
| SCHEMBL1691467 | 0.73 | MAOB (0.61) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL30703555 | 0.72 | MAOB (0.61) | MAOBNR4A2NR4A1NR4A3LMNA | |
| SCHEMBL1092594 | 0.72 | NR4A1 (0.70) | MAOBNR4A2NR4A1NR4A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077694-A1 | ARYL NITRONE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999059576-A1 | ARYL NITRONE THERAPEUTICS FOR THE TREATMENT OF INFLAMMATORY BOWEL DISEASE | CENTAUR PHARMACEUTICALS, INC. (US) | 1999-11-25 | — | — | WO | disclosed |