Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 19/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.53 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.53 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.53 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2892625 | 0.88 | CTSC (0.54) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL2892624 | 0.88 | CTSC (0.54) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL2884861 | 0.86 | CTSC (0.61) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL9888300 | 0.82 | CTSC (0.49) | CTSCKCNH2LTB4RLTB4R2 | |
| SCHEMBL9888342 | 0.82 | CTSC (0.50) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL2889502 | 0.80 | CTSC (0.81) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL2889507 | 0.80 | CTSC (0.81) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL2889383 | 0.79 | CTSC (0.64) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL2889385 | 0.79 | CTSC (0.64) | CTSCKCNH2LTB4RLTB4R2CTSK | |
| SCHEMBL7871672 | 0.77 | CTSS (0.44) | CTSCKCNH2LTB4RLTB4R2CTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010128324-A1 | SUBSTITUTED 1-CYANOETHYLHETEROCYCLYLCARBOXAMIDE COMPOUNDS 750 | ASTRAZENECA AB (SE) | 2010-11-11 | — | — | WO | disclosed |