Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536494 | 0.86 | KMT2A (0.50) | KMT2AMEN1METALDH1A1LMNA | |
| SCHEMBL6535829 | 0.86 | KMT2A (0.58) | KMT2AMEN1METL3MBTL1ALDH1A1 | |
| SCHEMBL13993102 | 0.77 | ALDH1A1 (0.38) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL11566827 | 0.71 | KMT2A (1.00) | KMT2AMEN1METL3MBTL1ALDH1A1 | |
| SCHEMBL30446303 | 0.71 | KMT2A (1.00) | KMT2AMEN1METL3MBTL1ALDH1A1 | |
| SCHEMBL2039879 | 0.71 | KMT2A (1.00) | KMT2AMEN1METL3MBTL1ALDH1A1 | |
| SCHEMBL4073038 | 0.70 | KMT2A (0.53) | KMT2AMEN1L3MBTL1ALDH1A1LMNA | |
| SCHEMBL10400093 | 0.69 | SRC (0.47) | KMT2AMEN1ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8885322 | 0.67 | KMT2A (0.77) | KMT2AMEN1KIF18AL3MBTL1ALDH1A1 | |
| SCHEMBL20898871 | 0.67 | HTR2A (0.54) | KMT2AMEN1L3MBTL1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6303630-B1 | TREATING HUMAN IMMUNODEFICIENCY VIRUS INFECTION BYADMINISTERING TO A HUMAN DIARYLSULFONE COMPOUND | UNIVERSITY OF THE SCIENCES IN PHILADELPHIA | 2001-10-16 | — | — | US | disclosed |
| US-6063790-A | TREATMENT OF AIDS | UNIVERSITY OF THE SCIENCES IN PHILADELPHIA (US) | 2000-05-16 | — | — | US | disclosed |