⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL28211134 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL7085472 | 0.97 | — | — | |
| Sulfuric Acid SCHEMBL28101970 | 0.84 | TP53 (0.31) | — | |
| SCHEMBL28090390 | 0.78 | — | — | |
| SCHEMBL27523351 | 0.73 | — | — | |
| SCHEMBL11851480 | 0.73 | — | — | |
| SCHEMBL7054555 | 0.73 | — | — | |
| SCHEMBL21089331 | 0.73 | — | — | |
| SCHEMBL28035563 | 0.71 | — | — | |
| SCHEMBL12738544 | 0.71 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4713389-A | Fungicidally and bactericidally active acylated saccharin derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1987-12-15 | — | — | US | claimed |
| US-12371454-B2 | Cyclic peptide compound having Kras inhibitory action | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2025-07-29 | — | — | US | disclosed |
| US-20240400617-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-12-05 | — | — | US | disclosed |
| US-20240148821-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-05-09 | — | — | US | disclosed |
| EP-4316503-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-02-07 | — | — | EP | disclosed |
| CN-117279655-A | Pharmaceutical use of cyclic peptide compounds | 中外制药株式会社 | 2023-12-22 | — | — | CN | disclosed |
| US-20230151060-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITORY ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-05-18 | — | — | US | disclosed |
| WO-2022234852-A1 | PHARMACEUTICAL USE OF CYCLIC PEPTIDE COMPOUND | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |
| EP-4043478-A1 | CYCLIC PEPTIDE COMPOUND HAVING KRAS INHIBITING ACTION | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2022-08-17 | — | — | EP | disclosed |
| US-20170183369-A1 | CATALYSTS AND METHODS FOR POLYMER SYNTHESIS | SAUDI ARAMCO TECHNOLOGIES COMPANY (SA) | 2017-06-29 | — | — | US | disclosed |
| US-20070232768-A1 | Alkoxyamines Containing a Radically Polymerizable Group | CIBA SPECIALTY CHEMICALS CORP. | 2007-10-04 | — | — | US | disclosed |
| US-7256165-B2 | Cleaning compositions | THE PROCTER & GAMBLE COMPANY (US) | 2007-08-14 | — | — | US | disclosed |
| US-20050183204-A1 | Fabric care composition for directly applying to fabrics | GUARIN LEDA M P (PH) | 2005-08-25 | — | — | US | disclosed |
| EP-1448198-A1 | NICOTIN-OR ISONICOTIN BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2004-08-25 | — | — | EP | disclosed |
| US-6620811-B2 | Adenosine receptor antagonists; nervous system and cardiovascular disorders; Parkinson*s, Huntington*s, and Alzheimer* disease; antiasthmatics, antiallergens | HOFFMANN-LA ROCHE INC. | 2003-09-16 | — | — | US | disclosed |
| US-20030134854-A1 | Isonicotin- and nicotinamide derivatives of benzothiazoles | F.HOFFMANN-LA ROCHE AG (CH) | 2003-07-17 | — | — | US | disclosed |
| WO-2003043636-A1 | NICOTIN-OR ISONICOTIN BENZOTHIAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-05-30 | — | — | WO | disclosed |
| EP-0101873-B1 | METHOD FOR MODIFYING UNSATURATED RUBBERS AND PRODUCT OBTAINED THEREBY | GENERAL ELECTRIC COMPANY (US) | 1987-09-16 | — | — | EP | disclosed |
| US-4517341-A | AMINE CATALYST | GENERAL ELECTRIC COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0101873-A2 | Method for modifying unsaturated rubbers and product obtained thereby | GENERAL ELECTRIC COMPANY (US) | 1984-03-07 | — | — | EP | disclosed |