Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.33 |
| ▸ | CA7 | P43166 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TOP1 | P11387 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29004607 | 0.84 | SMN1; SMN2 (0.45) | SMN1; SMN2NFE2L2PRMT1ALDH1A1CA12 | |
| SCHEMBL5270439 | 0.71 | SMN1; SMN2 (0.47) | SMN1; SMN2NFE2L2ALDH1A1CA12CA1 | |
| SCHEMBL6003080 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2NFE2L2PRMT1ALDH1A1CA12 | |
| SCHEMBL2094872 | 0.70 | SMN1; SMN2 (0.45) | SMN1; SMN2NFE2L2PRMT1ALDH1A1CA12 | |
| SCHEMBL2094349 | 0.69 | SMN1; SMN2 (0.48) | SMN1; SMN2NFE2L2PRMT1ALDH1A1CA12 | |
| Nitrogen SCHEMBL10986776 | 0.68 | SMN1; SMN2 (0.44) | SMN1; SMN2NFE2L2ALDH1A1CA12CA1 | |
| SCHEMBL2028142 | 0.68 | NFE2L2 (0.44) | SMN1; SMN2NFE2L2ALDH1A1CA12CA1 | |
| SCHEMBL25434306 | 0.67 | CA1 (0.61) | SMN1; SMN2NFE2L2ALDH1A1CA12CA1 | |
| SCHEMBL27753904 | 0.67 | CA1 (0.61) | SMN1; SMN2NFE2L2ALDH1A1CA12CA1 | |
| SCHEMBL151213 | 0.67 | CA1 (0.61) | SMN1; SMN2NFE2L2ALDH1A1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1069897-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 2001-01-24 | — | — | EP | claimed |
| WO-1999051227-A1 | METHODS FOR INHIBITING MRP1 | ELI LILLY AND COMPANY (US) | 1999-10-14 | — | — | WO | claimed |