Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862801 | 0.96 | CA2 (0.48) | EGFRCA2P4HTMALDH1A1HPGD | |
| SCHEMBL7867912 | 0.94 | EGFR (0.47) | EGFRP4HTMALDH1A1HPGDKDM4E | |
| SCHEMBL7867827 | 0.93 | KMT2A (0.42) | EGFRCA2P4HTMALDH1A1TSHR | |
| SCHEMBL7862739 | 0.92 | HPGD (0.47) | EGFRP4HTMALDH1A1LMNAHPGD | |
| SCHEMBL7870566 | 0.91 | EGFR (0.43) | EGFRCA2P4HTMALDH1A1TSHR | |
| SCHEMBL7871570 | 0.91 | EGFR (0.45) | EGFRP4HTMHPGDGABRA5KMT2A | |
| SCHEMBL7869460 | 0.91 | EGFR (0.43) | EGFRCA2P4HTMALDH1A1HPGD | |
| SCHEMBL9574842 | 0.91 | EGFR (0.43) | EGFRCA2P4HTMALDH1A1HPGD | |
| SCHEMBL7862723 | 0.90 | SMN1; SMN2 (0.44) | P4HTMLMNAGABRA5KMT2A | |
| SCHEMBL7871556 | 0.89 | CA2 (0.47) | EGFRCA2ALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |