Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.47 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.47 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.47 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.47 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.47 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.47 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.45 |
| ▸ | DRD4 | P21917 | 2/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497231 | 0.94 | DRD3 (0.52) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL7872993 | 0.93 | DRD3 (0.51) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL7861442 | 0.88 | PRKAA2 (0.53) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL8495206 | 0.87 | PRKAA2 (0.50) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL7869033 | 0.86 | PRKAA2 (0.49) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| Hydrochloric Acid SCHEMBL7861564 | 0.84 | PRKAA2 (0.49) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL7861462 | 0.84 | DRD3 (0.47) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL7861446 | 0.82 | DRD3 (0.55) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 | |
| SCHEMBL8494682 | 0.82 | SMN1; SMN2 (0.55) | ALDH1A1HTR1ASMN1; SMN2 | |
| SCHEMBL8494379 | 0.82 | ALDH1A1 (0.50) | DRD3ALDH1A1PRKAA2PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6306860-B1 | ANTIVIRAL ACTIVITIES AGAINST HEPATATIS B AS WELL AS HUMAN IMMUNODEFICIENCY VIRUS | DONG WHA PHARM. INC. CO., LTD. (KR) | 2001-10-23 | — | — | US | disclosed |
| WO-1999058526-A1 | NOVEL 2,5-PYRIDINEDICARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM. IND. CO., LTD. (KR) | 1999-11-18 | — | — | WO | disclosed |